Prof. Carlo Pappone

Chief of the Dept. of Electrophysiology – IRCCS Policlinico San Donato – San Donato Milanese (MI) Italy – Professor of Cardiology – Università Vita e Salute San Raffaele

My primary area of interest is the pathophysiology and treatment of patients with atrial fibrillation by interventional electrophysiology. The “Pappone approach” is currently one of the most used strategies to cure atrial fibrillation. I have been the principal investigator in many studies regarding the development and use of the CARTO electroanatomical mapping system for guiding ablation of atrial fibrillation in humans and the first one to perform a mapping study in a human patient in 1994. I have been author of landmark studies on radiofrequency transcatheter ablation for atrial fibrillation published for 3 consecutive years in Circulation, a leading journal in the field of cardiovascular medicine. These studies have been cited in 2.987 peerreviewed articles. Leading study entitled “Catheter ablation of atrial fibrillation using a 3D mapping system” has itself been cited in 315 articles, including the guidelines issued by the American Heart Association/American College of Cardiology/European Society of Cardiology for management of patients with atrial fibrillation.

My recent interest is focused on identification of patients with genetic diseases at risk of sudden death, such as Brugada syndrome patients, and more recently, on epicardial ablation to eliminate the Brugada syndome pattern. (JACC 2018, Circulation AE 2017, Circulation AE 2015, Eur Heart J 2009).